Publications
2023
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Dosta P, Cryer AM, Dion MZ, Shiraishi T, Langston SP, Lok D, Wang J, Harrison S, Hatten T, Ganno ML, Appleman VA, Munoz G, Puigmal N, Ferber S, Kalash S, Prado M, Rodriguez AL, Kamoun WS, Abu-Yousif AO, and Artzi N. "Investigation of the enhanced antitumor potency of STING agonist after conjugation to polymer nanoparticles." Nature Nanotechnology, 2023. https://doi.org/10.1038/s41565-023-01447-7.
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Freeman FE, Dosta P, Shanley LC, Tamez NR, Riojas CJ, Javelly OR, Mahon D, Kelly J, and Artzi N. "Localized Nanoparticle-Mediated Delivery of miR-29b Normalizes the Dysregulation of Bone Homeostasis Caused by Osteosarcoma", Advanced Materials, 2023. DOI: 10.1002/adma.202207877.
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Puigmal N, Ramos V, Artzi N, and Borros S. "Poly(β-amino ester)s-Based Delivery Systems for Targeted Transdermal Vaccination", Pharmaceutics, 2023 https://doi.org/10.3390/pharmaceutics15041262.
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Dion MZ and Artzi N. 2023. "Engineering Immunity to Disease Using Nanotechnology", Nanochemistry: Synthesis, Characterization and Applications, pp. 229-278, CRC Press.
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Dahis D, Dion MZ, Cryer AM, Dosta P, Gilboa T, Alonso M, Lewandowski M, Puigmal N, Munoz Taboad G, Azhari H, Ahmad R, Walt DR, and Artzi N. "Monitoring Melanoma Responses to STING Agonism and Focused Ultrasound Thermal Ablation Using Microneedles and Ultrasensitive Single Molecule Arrays", Advanced Functional Materials, 2023 https://doi.org/10.1002/adfm.202301659.
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Buriak MJ, Akinwande D, Artzi N, Brinker JC, Burrows C, Chan WCW, Chen C, Chen X, Chhowalla M, Chi L, Chueh W, Crudden CM, Di Carlo D, Glotzer SC, Hersam MC, Ho D, Hu TY, Huang J, Javey A, Kamat P V, Kim II-D, Kotov NA, LL TR, Lee YH, Luis YL, Liz-Marzan L, Mulvaney P, Narang P, Nordlander P, Oklu R, Parak WJ, Rogach AL, Salanne M, Samori P, Schaak R E, Scanze K S, Sekitani T, Skrabalak S, Sood AK, Votes I K, Wang S, Wang S, Wee A T S, Ye J. "Best Practices for Using AI When Writing Scientific Manuscripts: Caution, Care, and Consideration: Creative Science Depends on It." ACS Nano, 2023. https://doi.org/10.1021/acsnano.3c01544
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Dahis D, Azagury DM, Obeid F, Dion M, Cryer A, Alonso Riquelme M, Dosta P, Abraham A W, Gavish M, Artzi N. "Focused Ultrasound enhances brain delivery of sorafenib nanoparticles." Advanced Nanobiomed Research, 2023. https://doi.org/10.1002/anbr.202200142.
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Dosta P, Puigmal N, Cryer A M, Rodríguez AL, Scott E, Weissleder R, Mille MA, Artzi N. "Polymeric microneedle-based platform enables simultaneous delivery of cancer immunomodulatory drugs and detection of biomarkers in the skin." Theranostics, 2023. DOI: 10.7150/thno.73966.
2022
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Muñoz Taboada G, Dosta P, Edelman ER, Artzi N. "Sprayable Hydrogel for Instant Sealing of Vascular Anastomosis", Advanced Materials, 2022. https://doi.org/10.1002/adma.202203087.
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Freeman FE, Burdis R, Mahon OR, Kelly DJ, and Artzi N. "A Spheroid Model of Early and Late-Stage Osteosarcoma Mimicking the Divergent Relationship between Tumor Elimination and Bone Regeneration", Advanced Healthcare Materials, 2022. https://doi.org/10.1002/adhm.202101296.
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Ahmadi S, Sukprasert P, Vegesna R, Sinha S, Schischlik F, Arzi N, Khuller S, Schaffer AA, and Ruppin E. "The landscape of receptor-mediated precision cancer combination therapy via a single-cell perspective", Nature Communications, 2022. https://doi.org/10.1038/s41467-022-29154-2.
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Cryer AM and Artzi N. "Chapter Five - Engineered devices for tumor microenvironment immune modulation", Science Direct, 2022. https://doi.org/10.1016/B978-0-323-90949-5.00005-X.
2021
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Dahis D, Farti N, Romano R, Artzi N, and Azhari H. "Ultrasonic Thermal Monitoring of the Brain Using Golay Coded Excitations – Feasibility Study", IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, 2021 PDF.
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Puigmal N, Dosta P, Solhjou Z, Yatim K, Ramírez C, Choi JY, Haddad J, Cosme AP, Azzi J, and Artzi N. "Microneedle-Based Local Delivery of CCL22 and IL-2 Enriches Treg Homing to the Skin Allograft and Enables Temporal Monitoring of Immunotherapy Efficacy ", Advanced Functional Materials, 2021 PDF.
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Dosta P, Cryer A, Prado M, Dion M, Ferber S, Kalash S, and Artzi N. "Delivery of STING Agonist Using Polypeptide-Modified Dendrimer Nanoparticles in the Treatment of Melanoma", Advanced NanoBiomed Research, 2021 PDF.
2020
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Dosta P, Ferber S, Zhang Y, Wang K., Ros A, Uth N, Levinson Y, Abraham E, and Artzi N. "Scale-up Manufacturing of Gelatin-based Microcarriers for Cell Therapy" Journal of Biomedical Materials Research: Part B - Applied Biomaterials, 2020. PDF.
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Artzi N. “Materializing Personalized Medicine“, Advanced Materials, 2020. PDF.
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Muñoz Taboada G, Yang K, Pereira M, Liu S, Hu Y, Karp JM, Artzi N, and Lee Y. "Overcoming the translational barriers of tissue adhesives. Nature Review Materials 5, 310-329, 2020. PDF.
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Ahmadi S, Sukprasert P, Artzi N, Khuller S, Schaffer A, Ruppin E. “The Landscape of Precision Cancer Combination Therapy: A Single-Cell Perspective” BioRxiv, 2020, ,PDF.
2019
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Y. Zhang, P. Dosta, J. Conde, N. Oliva, M. Wang, and N. Artzi “Prolonged Local In Vivo Delivery of Stimuli-Responsive Nanogels That Rapidly Release Doxorubicin in TripleNegative Breast Cancer Cells”, Advanced Healthcare Materials, 2019 ,PDF.
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S. Ferber, R. J. Gonzalez, A. M. Cryer, U. H. von Andrian, and N. Artzi “Immunology-guided biomaterial design as mucosal cancer vaccine”, Advanced Materials, 2019.PDF.
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S. E. Strecker, S. Unterman, L. F. Charles, D. Pivovarchick, P. F. Maye, E. R. Edelman, and N. Artzi, “Osterix-mCherry Expression Allows For Early Bone Detection In A Calvarial Defect Model”, Advanced BioSystems, 2019. PDF
2017
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E. Abraham, O. Gadish, J. Franses, V. Chitalia, N Artzi, and E. Edelman. "Matrix-Embedded Endothelial Cells Attain a Progenitor-Like Phenotype" Advanced Biosystems, 2017. PDF
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G. Zhu, R. Falahat, K. Wang, A. Mailloux, N. Artzi and J Mulé. "Tumor-Associated Tertiary Lymphoid Structures: Gene-Expression Profiling and Their Bioengineering" Frontiers in Immunology, 2017. PDF
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N. Oliva, J. Conde, K. Wang, N. Artzi, "Designing Hydrogels for On-Demand Therapy.". Accounts of Chemical Research, 2017. PDF
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S. Unterman, L.F. Charles, S.E. Strecker, D. Kramarenko, D. Pivovarchik, E.R. Edelman, N. Artzi, "Hydrogel Nanocomposites with Independently Tunable Rheology and Mechanics.". ACS Nano, 2017. PDF
2016
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A. Gilam, J. Conde, D. Weissglas-Volkov, N. Oliva, E. Friedman, N. Artzi and N. Shomron, "Local microRNA delivery targets Palladin and prevents metastatic breast cancer". Nature Communications, 2016. PDF
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J. Conde, N. Oliva, Y. Zhang and N. Artzi, "Local triple-combination therapy results in tumour regression and prevents recurrence in a colon cancer model". Nature Materials, 2016. PDF Featured in Science Translational Medicine
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J. Conde, N. Shomron and N. Artzi, "Biomaterials for Metastasis: Bridging the Gap between Basic and Translational Research". Advanced Healthcare Materials (VIP paper), 2016. PDF
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J. Conde, N. Oliva and N. Artzi, "Revisiting the ‘one material fits all’ rule for cancer nanotherapy". Trends in Biotechnology, 2016. PDF
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H.S. Song, O.S. Kwon, J.H. Kim, J. Conde, N. Artzi, "3D Hydrogel Scaffold Doped With 2D Graphene Materials For Biosensors And Bioelectronics". Biosensors and Bioelectronics, 2016. PDF
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O.S. Kwon, H.S. Song, J. Conde, H. Kim, N. Artzi and J.H. Kim. "Dual-Color Emissive Upconversion Nanocapsules for Differential Cancer Bioimaging in vivo". ACS Nano, 2016. PDF
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Faucher KM, Artzi N, Beck M, Beckerman R, Moodie G, Albergo T, Conroy S, Dale A, Corbeil S, Martakos P, Edelman ER. "Tracking of Drug Release and Material Fate for Naturally Derived Omega-3 Fatty Acid Biomaterials". Annals of Biomedical Engineering, 2016. PDF
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J. Conde, N. OLiva, M. Atilano, H. S. Song and N. Artzi. "Self-assembled RNA-triple-helix hydrogel scaffold for microRNA modulation in the tumour microenvironment". Nature Materials, 15, 353-363, 2016. PDF Featured in Science Translational Medicine
2015
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N. Artzi, A.R. Tzafriri, K.M. Faucher, G. Moodie, T. Albergo, S. Conroy, S. Corbeil, P. Martakos, R. Virmani and E.R. Edelman. "Sustained efficacy and arterial drug retention by a fast drug eluting cross-linked fatty acid coronary stent coating". Annals of Biomedical Engineering, 2015. PDF
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S. Unterman*, A. Freiman, M. Beckerman, E. Abraham, J.R.L. Stanley, E. Levy, N. Artzi* and E. Edelman. "Tuning of collagen scaffold properties modulates embedded endothelial cell regulatory phenotype in repair of vascular injuries in vivo". Advanced Healthcare Materials, 2015. PDF
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J. Conde, C. Arnold, F. Tian and N. Artzi. "RNAi nanomaterials targeting immune cells as an anti-tumor therapy: the missing link in cancer treatment?". Materials Today, 2015. PDF
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C. Bao, J. Conde, J. Curtin, N. Artzi, F. Tian and D. Cui. "Bioresponsive antisense DNA gold nanobeacons as a hybrid in vivo theranostics platform for the inhibition of cancer cells and metastasis". Scientific Reports, 5, 12297, 2015. PDF
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J. Conde, C. Bao, Y. Tan, D. Cui, E.R. Edelman, H.S. Azevedo, H.J. Byrne, N. Artzi and F. Tian. "Dual targeted immunotherapy via in vivo delivery of biohybrid RNAi-peptide nanoparticles to tumour-associated macrophages and cancer cells". Advanced Functional Materials, 2015. PDF
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J. Conde & N. Artzi. "The next generation of smart gold nanobeacons: nanotheranostics is ready for prime-time". Nanomedicine (Lond.), 10, 1535-1538, 2015. PDF
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N. Oliva, S. Unterman, Y. Zhang, J. Conde, H. S. Song and N. Artzi. "Personalizing biomaterials for precision nanomedicine in light of local tissue microenvironment". Advanced Healthcare Materials, 2015. PDF
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J. Conde, N. Oliva and N. Artzi. “Implantable hydrogel embedded dark-gold nanoswitch as a theranostics probe to sense and overcome cancer multidrug resistance”. PNAS, 112, 1278-1287, 2015. PDF Featured in Nature Reviews Drug Discovery PDF
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J. Conde & N. Artzi. "Are RNAi and miRNA therapeutics truly dead?". Trends in Biotechnology, 33, 141-144, 2015, PDF
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A. Tzur-Balter, Z. Shatsberg, M. Beckerman, E. Segal and N. Artzi “Mechanism of Erosion of Nanostructured Porous Si Drug Carriers in Neoplastic Tissues”. Nature Communications, 6, 2015. PDF
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N. Oliva, M. Carcole, R. Beckerman, A. Hayward, B. Stanley, N. Parry, E.R. Edelman and N. Artzi. "Regulation of dendrimer:dextran material performance by the altered tissue microenvironment in inflammation and neoplasia". Sci Trans Med, 7, 272ra11, 2015. Featured in Science Translational Medicine. PDF
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J. Conde, E.R. Edelman, N. Artzi. "Target-responsive DNA/RNA nanomaterials for microRNA sensing and inhibition: The jack-of-all-trades in cancer nanotheranostics?" Adv Drug Deliv Rev., 81, 169-183, 2015. PDF
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A. French, C. Bravery, J. Smith, A. Chandra, P. Archibald, J.D. Gold, N. Artzi, H.W. Kim, R.W. Barker, A. Meissner, J.C. Wu, J.C. Knowles, D. Williams, G. García-Cardeña, D. Sipp, S. Oh, J.F. Loring, M.S. Rao, B. Reeve, I. Wall, A.J. Carr, K. Bure, G. Stacey, J.M. Karp, E.Y. Snyder, D.A. Brindley. "Enabling Consistency in Pluripotent Stem Cell-Derived Products for Research and Development and Clinical Applications Through Material Standards." Stem Cells Transl Med. 2015. PDF
2014 and prior
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N. Segovia, M. Pont, N. Oliva, V. Ramos, S. Borrós, N. Artzi. "Hydrogel Doped with Nanoparticles for Local Sustained Release of siRNA in Breast Cancer". Adv Healthc Mater., 2014, 4, 271-280. PDF
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N. Artzi & E. Edelman. “Aldehyde-Amine Chemistry Enables Tissue Adhesive Materials to Respond to Physiologic Variation and Pathologic States”, Israel Journal of Chemistry, 53 (9-10), 748-755, 2013. PDF
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N. Oliva, S. Shitreet, E. Abraham, B. Stanley, E.R. Edelman, N. Artzi. "Natural tissue microenvironmental conditions modulate adhesive material performance". Langmuir, 28(43), 15402-9, 2012. PDF
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N. Artzi, A. Zeiger, F. Boehning, A. Bon Ramos, K. Van Vliet, E. R. Edelman. “Tuning adhesion failure strength for tissue-specific applications”. Acta Biomater, 7(1), 67-74, 2011. PDF
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N. Artzi, N. Oliva, C. Puron, S. Shitreet, S. Artzi, A. bon Ramos, A. Groothuis, G. Sahagian, E.R. Edelman. "In vivo and in vitro tracking of erosion in biodegradable materials using non-invasive fluorescence imaging". Nature Materials, 10(9), 704-9, 2011. PDF
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N. Artzi, T. Shazly, A. Baker, A. Bon, and E. Edelman “Aldehyde-Amine Chemistry Enables Modulated Biosealants with Tissue-Specific Adhesion”, Advanced Materials, 21(32- 33), 3399-3403, 2009. Featured in Nature Medicine. PDF
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N. Artzi, T. Shazly, C. Crespo, and E. Edelman “Characterization of Star Adhesive Sealant Based on PEG: Dextran Hydrogels”, Macromolecular Bioscience, 9(8), 754-765, 2009. PDF
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T. Shazly, N. Artzi, F. Boehning, and E. Edelman “Viscoelastic Adhesive Mechanics of Aldehyde-Mediated Soft Tissue Sealants”, Biomaterials, 29(35), 4584-4591, 2008. PDF
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N. Artzi, B. B. Khatua, Narkis and A. Siegmann, “Studies on nylon-6/EVOH/clay ternary composites”, Polymer Composites, 27(1), 15-23, 2006. PDF
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N. Artzi, “Why Nano-Composites Are In? A Glimpse Into Polymer Based Nanocomposites”, Reviews in Chemical Engineering, 21(5), 307-345, 2005.
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D. Aleperstein, N. Artzi,A. Siegmann, and M. Narkis, “Experimental and Computational Investigation of EVOH/clay Nanocomposites”, Journal of Applied Polymer Science, 97(5), 2060-2066, 2005. PDF
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N. Artzi, M. Narkis, and A. Siegmann, “EVOH/clay Nanocomposite Systems: Processing, Structure, Property Relationships”, Annual Technical Conference - Society of Plastics Engineers, 63rd, 1461-1465, 2005.
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N. Artzi, M. Narkis, and A. Siegmann, “Review of Melt-Processed EVOH/organoclay Nanocomposites”, J. Polym. Sci., Part B:Polymer Physics, 43(15), 1931- 1943, 2005. PDF
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N. Artzi, A. Tzur, M. Narkis, and A. Siegmann, “The Effect of Extrusion Processing Conditions on EVOH/clay Nanocomposites at Low Organo-Clay Contents”, Polymer Composites, 26(3), 343-351, 2005. PDF
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N. Artzi, B.B. Khatua, R. Tchoudakov, M. Narkis, A, Berner, A. Siegmann, J.M. Lagaron, “Physical and Chemical Interactions in Melt Mixed Nylon-6/EVOH Blends”, J. Macromol. Sci., Part B: Phys., B43(3), 605-624, 2004.
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N. Artzi, M. Narkis, and A. Siegmann, “EVOH/clay Nanocomposites Produced by Dynamic Melt Mixing”, Polym. Eng. Sci., 44(6), 1019-1026, 2004. PDF
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N. Artzi, Y. Nir, M. Narkis, and A. Siegmann, “The Effect of Maleated Compatibilizers on the Structure and Properties of EVOH/Clay Nanocomposites”, Polymer Composites, 24, 627-639, 2003. PDF
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N. Artzi, Y. Nir, M. Narkis, and A. Siegmann, “Melt Blending of EVOH/Clay nanocomposites: Effect of Clay Type and Processing Conditions”, J. Polym. Sci., Part B:Polymer Physics, 40, 1741-1753, 2002. PDF
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N. Artzi, Y. Nir, D. Wang, M. Narkis, and A. Siegmann, “EVOH/Clay Nanocomposites Produced by Melt Processing”, Polymer Composites, 22, 710-720, 2001. PDF