Award image
Award image

Micrograph of a microneedle patch

Microneedle patch
Microneedle patch

Fluorescent labeled Microneedle patch loaded with drug

The miRNA bouquet
The miRNA bouquet

RNA triple-helix microparticles embedded on an hydrogel

Gold nanoparticles internalization
Gold nanoparticles internalization

Breast cancer cells (in red) internalized with miRNA-gold nanoparticles (in green)

Local triple therapy in action
Local triple therapy in action

Patch that delivers drug, gene, and light-based therapy to tumor sites shows promising results

Glue tissues with smart adhesives
Glue tissues with smart adhesives

Dendrimer/dextran adhesive (green, tagged with fluorescein) morphology on the colon serosal layer (red) of healthy rat.

In vivo angiogenesis
In vivo angiogenesis

Red- dendrimer (incorporated by Macrophages); Blue- Vessels; Green - Macrophages

Endothelial Gelfoam
Endothelial Gelfoam

Gelatin embedded with endothelial cells inhibit smooth muscle cells proliferation. GFP-ECs seeded Gelfoam in a mouse carotid artery

ydrogel on triple combination therapy
ydrogel on triple combination therapy

Tumor tissue impregnated with smart gold nanorods (in green) and gold nanospheres (in red)

Cellular Infiltration of Hydrogel
Cellular Infiltration of Hydrogel

Cells (blue) migrate into dextran/dendrimer hydrogel (green) in an in vivo mouse model

Osterix Cherry Mouse Skull Focus
Osterix Cherry Mouse Skull Focus

Osterix expression seen in the calvarium in two day old neonates

Tissue-Hydrogel interactions
Tissue-Hydrogel interactions

Immunofluorescence staining against collagen, for both basement membrane collagen and serosal collagen performed in rabbits using healthy tissue

Calvarial defect
Calvarial defect

Masson's Trichrome staining showing cellular infiltrates into a filled critical sized calvarial defect four weeks post surgery

Gene Silencing with smart siRNA NPs
Gene Silencing with smart siRNA NPs

Delivery of siRNA gold nanoparticles to colorectal cancer cell

Focal cartilage defect
Focal cartilage defect

Disorganized tissue repair and reduced GAG expression as seen 4 weeks post surgery

Gold NanoRods
Gold NanoRods

Gold nanorods coated with PEG and a monoclonal antibody

Hydrogel doped with Gold Nanobeacons
Hydrogel doped with Gold Nanobeacons

Implantable hydrogel embedded dark-gold nanoswitch as a theranostic probe to sense and overcome cancer multidrug resistance