Award image
Award image

Micrograph of a microneedle patch

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Microneedle patch
Microneedle patch

Fluorescent labeled Microneedle patch loaded with drug

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The miRNA bouquet
The miRNA bouquet

RNA triple-helix microparticles embedded on an hydrogel

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Gold nanoparticles internalization
Gold nanoparticles internalization

Breast cancer cells (in red) internalized with miRNA-gold nanoparticles (in green)

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Local triple therapy in action
Local triple therapy in action

Patch that delivers drug, gene, and light-based therapy to tumor sites shows promising results

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Glue tissues with smart adhesives
Glue tissues with smart adhesives

Dendrimer/dextran adhesive (green, tagged with fluorescein) morphology on the colon serosal layer (red) of healthy rat.

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In vivo angiogenesis
In vivo angiogenesis

Red- dendrimer (incorporated by Macrophages); Blue- Vessels; Green - Macrophages

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Endothelial Gelfoam
Endothelial Gelfoam

Gelatin embedded with endothelial cells inhibit smooth muscle cells proliferation. GFP-ECs seeded Gelfoam in a mouse carotid artery

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ydrogel on triple combination therapy
ydrogel on triple combination therapy

Tumor tissue impregnated with smart gold nanorods (in green) and gold nanospheres (in red)

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Cellular Infiltration of Hydrogel
Cellular Infiltration of Hydrogel

Cells (blue) migrate into dextran/dendrimer hydrogel (green) in an in vivo mouse model

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Osterix Cherry Mouse Skull Focus
Osterix Cherry Mouse Skull Focus

Osterix expression seen in the calvarium in two day old neonates

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Tissue-Hydrogel interactions
Tissue-Hydrogel interactions

Immunofluorescence staining against collagen, for both basement membrane collagen and serosal collagen performed in rabbits using healthy tissue

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Calvarial defect
Calvarial defect

Masson's Trichrome staining showing cellular infiltrates into a filled critical sized calvarial defect four weeks post surgery

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Gene Silencing with smart siRNA NPs
Gene Silencing with smart siRNA NPs

Delivery of siRNA gold nanoparticles to colorectal cancer cell

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Focal cartilage defect
Focal cartilage defect

Disorganized tissue repair and reduced GAG expression as seen 4 weeks post surgery

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Gold NanoRods
Gold NanoRods

Gold nanorods coated with PEG and a monoclonal antibody

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Hydrogel doped with Gold Nanobeacons
Hydrogel doped with Gold Nanobeacons

Implantable hydrogel embedded dark-gold nanoswitch as a theranostic probe to sense and overcome cancer multidrug resistance

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